SCHEMBL27767007

SCHEMBL27767007

c1ccc2c(-c3ncc[nH]3)c3ccccc3cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 6/20 0.50
NISCH Q9Y2I1 3/20 0.50
MTOR P42345 1/20 0.50
ADK P55263 1/20 0.50
ADRA2B P18089 5/20 0.43
ADRA2C P18825 5/20 0.43
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CSNK1A1 P48729 1/20 0.39
TYRO3 Q06418 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
IDO1 P14902 1/20 0.39
ALOX5 P09917 1/20 0.37
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7397776 0.81 MAPT (0.50) ADRA2ANISCHMTORADKADRA2B
SCHEMBL14886220 0.80 CSNK1A1 (0.53) ADRA2ANISCHMTORADKADRA2B
SCHEMBL21298118 0.80 ADRA2A (0.49) ADRA2ANISCHMTORADKADRA2B
SCHEMBL3053174 0.80 ADRA2A (0.46) ADRA2ANISCHMTORADKADRA2B
SCHEMBL8342759 0.80 ADRA2A (0.46) ADRA2ANISCHMTORADKADRA2B
SCHEMBL28270082 0.78 NISCH (0.50) ADRA2ANISCHMTORADKADRA2B
SCHEMBL4721867 0.77 ADRA2A (0.46) ADRA2ANISCHMTORADKADRA2B
SCHEMBL9682527 0.77 NISCH (0.54) ADRA2ANISCHMTORADKADRA2B
SCHEMBL27945010 0.76 NISCH (0.50) ADRA2ANISCHMTORADKADRA2B
SCHEMBL27843956 0.76 NISCH (0.53) ADRA2ANISCHMTORADKADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103788130-B A kind of synthetic method of diphenylphosphine imidazoles of novel phosphorus-containing organic ligand 1 (9 anthryl) 2 and application 南开大学 2018-04-10 CN claimed
CN-103788130-A Novel synthesis method and applications of phosphorus-containing organic ligand 1-(9-anthracen)-2-diphenylphosphino-imidazole UNIV NANKAI 2014-05-14 CN claimed
CN-103788130-B A kind of synthetic method of diphenylphosphine imidazoles of novel phosphorus-containing organic ligand 1 (9 anthryl) 2 and application 南开大学 2018-04-10 CN disclosed
CN-103788130-A Novel synthesis method and applications of phosphorus-containing organic ligand 1-(9-anthracen)-2-diphenylphosphino-imidazole UNIV NANKAI 2014-05-14 CN disclosed
CN-101475597-B Preparation and use of ruthenium and iridium metal complex singlet oxygen fluorescent probe UNIV BEIJING NORMAL 2011-11-16 CN disclosed
CN-102236259-A Radiation sensitivity resin composition for display element, interlayer insulation film, protective film and spacer and forming method thereof JSR CORP 2011-11-09 CN disclosed
CN-101475597-A Preparation and use of ruthenium and iridium metal complex singlet oxygen fluorescent probe UNIV BEIJING NORMAL (CN) 2009-07-08 CN disclosed