Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.31 |
| ▸ | BCL2L11 | O43521 | 4/20 | 0.31 |
| ▸ | BCL2 | P10415 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27853000 | 0.88 | POLB (0.40) | TDP1 | |
| SCHEMBL22901859 | 0.86 | LTA4H (0.37) | LMNAHTTLTA4HMCL1BCL2L11 | |
| Tert-Butyl Formate SCHEMBL27767281 | 0.82 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27853012 | 0.76 | TDP1 (0.35) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27651272 | 0.73 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28052001 | 0.73 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28312695 | 0.73 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27615609 | 0.73 | SLC6A4 (0.38) | SSTR4TDP1 | |
| SCHEMBL15358952 | 0.72 | PLG (0.46) | — | |
| SCHEMBL3068478 | 0.72 | POLB (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459246-B | Isoxazol-3 (2H) -one analogs as therapeutic agents | ASTRAZENECA AB | 2014-05-07 | — | — | CN | disclosed |