Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL28881233 | 0.92 | PTPN2 (0.42) | PTPN2PTPN1AXLLMNANPSR1 | |
| SCHEMBL930387 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL2269210 | 0.90 | PTPN2 (0.46) | PTPN2PTPN1AXLLMNANPSR1 | |
| SCHEMBL27691586 | 0.90 | PTPN2 (0.46) | PTPN2PTPN1AXLLMNANPSR1 | |
| Isopropyl Alcohol SCHEMBL28985050 | 0.82 | AXL (0.43) | PTPN2PTPN1AXLLMNANPSR1 | |
| Benzoic Acid SCHEMBL9555786 | 0.81 | TSHR (0.52) | PTPN2PTPN1AXLLMNANPSR1 | |
| SCHEMBL56103 | 0.74 | — | — | |
| SCHEMBL28163842 | 0.72 | — | — | |
| SCHEMBL1353374 | 0.72 | — | — | |
| SCHEMBL1493596 | 0.71 | PTPN2 (0.44) | PTPN2PTPN1AXLLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101619042-B | Method for synthesizing aromatic pyrimidine-4(3H)-ketone compounds | UNIV ZHEJIANG TECHNOLOGY | 2011-11-09 | — | — | CN | disclosed |
| CN-101619042-A | Method for synthesizing aromatic pyrimidine-4(3H)-ketone compounds | UNIV ZHEJIANG TECHNOLOGY | 2010-01-06 | — | — | CN | disclosed |