⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930387 | 0.81 | — | — | |
| SCHEMBL1353374 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL2269210 | 0.79 | PTPN2 (0.46) | — | |
| SCHEMBL10738874 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL14985248 | 0.76 | — | — | |
| SCHEMBL7414624 | 0.76 | — | — | |
| SCHEMBL1366984 | 0.76 | — | — | |
| SCHEMBL2889862 | 0.76 | MAPT (0.61) | — | |
| SCHEMBL7950185 | 0.76 | — | — | |
| SCHEMBL2225907 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250302831-A1 | THERAPY FOR ALCOHOL-RELATED LIVER DISEASE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, OFFICE OF THE GENERAL COUNSEL (024) | 2025-10-02 | — | — | US | claimed |
| CN-117820337-A | Preparation method of 12H-benzo [4,5] thiazolo [2,3-b ] quinazoline 12-ketone compound | 赣南师范大学 | 2024-04-05 | — | — | CN | claimed |
| WO-2022226078-A1 | THERAPY FOR ALCOHOL-RELATED LIVER DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-10-27 | — | — | WO | claimed |
| CN-113856495-A | Asymmetric polyether sulfone filter membrane for virus removal and preparation method thereof | 杭州科百特过滤器材有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-108658999-B | Synthesis method of 2-phenyl heterocyclic [2,3-d ] pyrimidine-4 (3H) -ketone compound | 温州大学 | 2021-02-05 | — | — | CN | claimed |
| CN-108358949-A | The preparation method of 2,4- of one kind dichloro-thiophenes simultaneously [3,2-D] pyrimidine | 南京法恩化学有限公司 | 2018-08-03 | — | — | CN | claimed |
| US-8354444-B2 | Substituted pyrrolidine-2-carboxamides | HOFFMANN-LA ROCHE INC. (US) | 2013-01-15 | — | — | US | claimed |
| EP-2340021-B1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | HOFFMANN LA ROCHE (CH) | 2012-11-07 | — | — | EP | claimed |
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-17 | — | — | US | claimed |
| US-20100120780-A1 | TREATMENTS FOR PREMATURE EJACULATION IN HUMANS | TRINITY LABORATORIES INC. | 2010-05-13 | — | — | US | claimed |
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | DING QINGJIE | 2010-03-25 | — | — | US | claimed |
| WO-2010031713-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | claimed |
| WO-2008131256-A1 | IMPROVED TREATMENTS FOR PREMATURE EJACULATION IN HUMANS | TRINITY LABORATORIES INC. (US) | 2008-10-30 | — | — | WO | claimed |
| EP-1888060-A2 | NK-B INHIBITORS FOR THE TREATMENT OF MUSCULAR DYSTROPHY | A. T. Still University of Health Sciences (US) | 2008-02-20 | — | — | EP | claimed |
| US-20060280812-A1 | Compositions and methods for the treatment of muscular dystrophy | A.T. STILL UNIVERSITY OF HEATH SCIENCES | 2006-12-14 | — | — | US | claimed |
| WO-2006127930-A2 | NK-B INHIBITORS FOR THE TREATMENT OF MUSCULAR DYSTROPHY | A. T. STILL UNIVERSITY OF HEALTH SCIENCES (US) | 2006-11-30 | — | — | WO | claimed |
| CN-119857534-A | Preparation method of foam copper-based catalytic material for electrochemical degradation of chloramphenicol sewage | 北方工业大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-119798275-A | Preparation method of 2, 4-dichloro-thieno [3,2, d ] pyrimidine | 安徽尖峰北卡药业有限公司 | 2025-04-11 | — | — | CN | disclosed |
| WO-1993008170-A1 | SUBSTITUTED HETEROCYCLES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-29 | — | — | WO | disclosed |
| US-5187168-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |