Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 13/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27613139 | 0.99 | CCR5 (0.48) | CCR5OPRM1TP53TMEM97 | |
| SCHEMBL341726 | 0.88 | CCR5 (0.50) | CCR5OPRM1TMEM97 | |
| SCHEMBL342314 | 0.88 | HTR2A (0.54) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL10322270 | 0.87 | HTR2A (0.53) | CCR5OPRM1 | |
| SCHEMBL339715 | 0.87 | HTR2A (0.56) | CCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL10322521 | 0.86 | HTR2A (0.56) | CCR5OPRM1 | |
| SCHEMBL342207 | 0.85 | OPRM1 (0.52) | CCR5OPRM1TP53TMEM97 | |
| SCHEMBL4915049 | 0.85 | HTR2A (0.54) | TP53 | |
| Hydrochloric Acid SCHEMBL4211246 | 0.84 | HTR2A (0.53) | TP53 | |
| Cadaverine Tartrate SCHEMBL10322706 | 0.84 | CCR5 (0.48) | CCR5OPRM1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101619057-A | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARM INC | 2010-01-06 | — | — | CN | claimed |