Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GNRHR | P30968 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681877 | 0.87 | GNRHR (0.49) | ALOX5MAPTSMN1; SMN2GNRHRHTT | |
| SCHEMBL6676086 | 0.85 | NPBWR1 (0.54) | ALOX5ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL12227518 | 0.84 | CYP19A1 (0.46) | ALOX5ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL12330621 | 0.82 | ALOX5 (0.48) | ALOX5ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL16307013 | 0.82 | ALOX5 (0.49) | ALOX5ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL31455922 | 0.81 | MAPT (0.45) | ALOX5ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL399470 | 0.81 | ALOX5 (0.47) | ALOX5ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL2858710 | 0.81 | ALOX5 (0.47) | ALOX5ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL5413213 | 0.81 | MEN1 (0.52) | ALOX5ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL31758898 | 0.81 | DDR1 (0.45) | MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611019-A | The big ring serum prothrombin conversion accelerator (SPCA) a inhibitor that can be used as anticoagulant | BRISTOL MYERS SQUIBB CO (US) | 2009-12-23 | — | — | CN | disclosed |