Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2773533 | 0.99 | GPR119 (0.45) | GPR119CHRM4CYP4F2CYP4A11MAPT | |
| Hydrochloric Acid SCHEMBL2772948 | 0.86 | GPR119 (0.45) | GPR119CHRM4CYP4F2CYP4A11ACACB | |
| Hydrochloric Acid SCHEMBL2777904 | 0.85 | CHRM4 (0.45) | GPR119CHRM4CYP4F2CYP4A11ACACB | |
| SCHEMBL2775675 | 0.84 | EPHX2 (0.52) | MAPTNAMPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2774990 | 0.84 | LIPE (0.56) | GPR119CYP4F2CYP4A11ACACBPIK3CD | |
| SCHEMBL2776309 | 0.83 | ACACB (0.46) | GPR119CHRM4CYP4F2CYP4A11MAPT | |
| Hydrochloric Acid SCHEMBL2775304 | 0.83 | EPHX2 (0.51) | MAPTNAMPTALDH1A1 | |
| SCHEMBL6522441 | 0.81 | GPR119 (0.41) | GPR119CHRM4CYP4F2CYP4A11MAPT | |
| SCHEMBL2775725 | 0.81 | DPP4 (0.49) | NAMPTSRD5A1 | |
| Hydrochloric Acid SCHEMBL2776438 | 0.80 | SRD5A1 (0.46) | GPR119PIK3CDNAMPTALDH1A1SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |