Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793167 | 0.81 | TSHR (0.52) | SLC22A6TSHRAKR1B1GPR84PPARG | |
| Acetic Acid SCHEMBL20657787 | 0.80 | FFAR3 (0.39) | TSHRALDH1A1TDP1HSD17B10LMNA | |
| SCHEMBL6242801 | 0.79 | LMNA (0.44) | SLC22A6TSHRAKR1B1GPR84PPARG | |
| SCHEMBL2682110 | 0.78 | AKR1B1 (0.43) | SLC22A6TSHRAKR1B1GPR84PPARG | |
| Glutarate SCHEMBL28572304 | 0.78 | SLC22A6 (0.58) | SLC22A6TSHRAKR1B1GPR84PPARG | |
| SCHEMBL8400588 | 0.77 | ALDH1A1 (0.50) | SLC22A6TSHRAKR1B1GPR84PPARG | |
| SCHEMBL791222 | 0.77 | LMNA (0.50) | SLC22A6TSHRAKR1B1GPR84PPARG | |
| SCHEMBL26397513 | 0.76 | TSHR (0.52) | SLC22A6TSHRGPR84PPARGPPARD | |
| Glutarate SCHEMBL28037031 | 0.75 | SLC22A6 (0.61) | SLC22A6TSHRAKR1B1GPR84PPARG | |
| Adipic Acid SCHEMBL5716572 | 0.75 | AKR1B1 (0.62) | SLC22A6TSHRAKR1B1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101624609-B | Method for preparing (S)-3-substituent glutaric acid monoester class compound by enzyme catalysis | ZHEJIANG JIUZHOU PHARM CO LTD | 2013-04-17 | — | — | CN | claimed |
| CN-101624609-B | Method for preparing (S)-3-substituent glutaric acid monoester class compound by enzyme catalysis | ZHEJIANG JIUZHOU PHARM CO LTD | 2013-04-17 | — | — | CN | disclosed |
| CN-101624609-A | Method for preparing (S)-3-substituent glutaric acid monoester class compound by enzyme catalysis | ZHEJIANG JIUZHOU PHARMACEUTICA | 2010-01-13 | — | — | CN | disclosed |