Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451995 | 0.79 | ACHE (0.43) | ACHEMAPTPKMHTR2CSSTR1 | |
| SCHEMBL3936577 | 0.76 | SLC7A5 (0.41) | MAPTPKMSSTR1SSTR4ALDH1A1 | |
| SCHEMBL1793285 | 0.74 | ACHE (0.52) | ACHEHTR2CKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1789986 | 0.73 | ACHE (0.51) | ACHEHTR2CKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10782553 | 0.71 | ACHE (0.71) | ACHEMAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12652935 | 0.70 | MAPT (0.71) | MAPTPKMHTR2CALDH1A1SLC9A1 | |
| SCHEMBL12617862 | 0.70 | MAPT (0.71) | MAPTPKMHTR2CALDH1A1SLC9A1 | |
| SCHEMBL19341986 | 0.70 | KDM1A (0.50) | MAPTPKMSLC6A2SLC6A4 | |
| SCHEMBL19908542 | 0.70 | KDM1A (0.50) | MAPTPKMSLC6A2SLC6A4 | |
| SCHEMBL11444965 | 0.69 | ACHE (0.69) | ACHEMAPTKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |