Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768004 | 0.79 | ACHE (0.47) | ACHEHTR2CSSTR1SSTR4KMT2A | |
| SCHEMBL30075780 | 0.78 | SSTR1 (0.47) | HTR2CSSTR1SSTR4 | |
| SCHEMBL23858278 | 0.78 | SSTR1 (0.47) | HTR2CSSTR1SSTR4 | |
| SCHEMBL23858281 | 0.78 | SSTR1 (0.47) | HTR2CSSTR1SSTR4 | |
| SCHEMBL23858279 | 0.78 | SSTR1 (0.47) | HTR2CSSTR1SSTR4 | |
| SCHEMBL13406406 | 0.77 | KMO (0.49) | SSTR1SSTR4MAPTPKM | |
| SCHEMBL13406404 | 0.77 | KMO (0.49) | SSTR1SSTR4MAPTPKM | |
| SCHEMBL13406472 | 0.77 | KMO (0.49) | SSTR1SSTR4MAPTPKM | |
| SCHEMBL13406405 | 0.77 | KMO (0.49) | SSTR1SSTR4MAPTPKM | |
| SCHEMBL13406407 | 0.77 | KMO (0.49) | SSTR1SSTR4MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615699-B1 | BENZOXAZINYL-AMIDOCYCLOPENTYL-HETEROCYCLIC MODULATORS OF CHEMOKINE RECEPTORS | MERCK SHARP & DOHME (US) | 2010-03-24 | — | — | EP | disclosed |