Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27768033 | 0.94 | GPR119 (0.43) | GPR119HTTNPC1RAB9AMEN1 | |
| Tert-Butyl Formate SCHEMBL28781308 | 0.90 | GPR119 (0.44) | GPR119HTTNPC1RAB9AMEN1 | |
| Tert-Butyl Formate SCHEMBL27768398 | 0.88 | GPR119 (0.44) | GPR119AOC3EPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL28784622 | 0.86 | GPR119 (0.41) | GPR119HTTNPC1RAB9AMEN1 | |
| Tert-Butyl Formate SCHEMBL27973831 | 0.86 | GPR119 (0.45) | GPR119HTTNPC1RAB9AMEN1 | |
| Tert-Butyl Formate SCHEMBL27768095 | 0.84 | GPR119 (0.46) | GPR119NPC1RAB9ALMNAMAPT | |
| Tert-Butyl Formate SCHEMBL27973923 | 0.84 | GPR119 (0.41) | GPR119HTTNPC1RAB9AMEN1 | |
| Tert-Butyl Formate SCHEMBL27789571 | 0.84 | GPR119 (0.47) | GPR119HTTNPC1RAB9AMEN1 | |
| Tert-Butyl Formate SCHEMBL27768039 | 0.83 | GPR119 (0.52) | GPR119RAB9AMEN1KMT2AAOC3 | |
| Tert-Butyl Formate SCHEMBL27768213 | 0.83 | AOC3 (0.46) | GPR119NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101616586-B | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders | CYMABAY THERAPEUTICS INC | 2014-08-13 | — | — | CN | claimed |
| CN-101616586-B | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders | CYMABAY THERAPEUTICS INC | 2014-08-13 | — | — | CN | disclosed |
| CN-102026636-B | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2014-07-16 | — | — | CN | disclosed |
| CN-102026636-A | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2011-04-20 | — | — | CN | disclosed |
| CN-101616586-A | The heterocyclic receptor agonists of treatment diabetes and metabolic disorder | METABOLEX INC | 2009-12-30 | — | — | CN | disclosed |