Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28784619 | 0.93 | BAZ2A (0.40) | AOC3BAZ2AEPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL27873798 | 0.88 | AOC3 (0.46) | AOC3BAZ2AEPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL27873726 | 0.88 | AOC3 (0.48) | AOC3BAZ2AEPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL27789574 | 0.88 | KDM4E (0.35) | AOC3BAZ2ASLC6A3RAB9AKDM4E | |
| Tert-Butyl Formate SCHEMBL27768030 | 0.87 | BAZ2A (0.42) | AOC3BAZ2AEPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL27971425 | 0.85 | AOC3 (0.51) | AOC3BAZ2AEPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL27768122 | 0.83 | GPR119 (0.43) | AOC3EPHA2KDREPHB4HPGDS | |
| Tert-Butyl Formate SCHEMBL27975189 | 0.82 | AOC3 (0.41) | AOC3BAZ2AEPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL28781308 | 0.81 | GPR119 (0.44) | AOC3BAZ2AEPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL27789576 | 0.80 | AOC3 (0.40) | AOC3BAZ2AEPHA2KDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101616586-B | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders | CYMABAY THERAPEUTICS INC | 2014-08-13 | — | — | CN | disclosed |
| CN-102026636-B | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2014-07-16 | — | — | CN | disclosed |
| CN-102026636-A | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2011-04-20 | — | — | CN | disclosed |
| CN-101616586-A | The heterocyclic receptor agonists of treatment diabetes and metabolic disorder | METABOLEX INC | 2009-12-30 | — | — | CN | disclosed |