Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279785 | 0.93 | KCNH2 (0.47) | RAB9APOLBDRD4DRD3PDE10A | |
| SCHEMBL27789661 | 0.89 | TAAR1 (0.46) | RAB9APOLBDRD4DRD3PDE10A | |
| SCHEMBL28114539 | 0.84 | RAB9A (0.53) | RAB9APOLBDRD4DRD3NPY5R | |
| SCHEMBL27478837 | 0.82 | RAB9A (0.52) | RAB9APOLBDRD4DRD3NPC1 | |
| SCHEMBL27789960 | 0.80 | TNIK (0.56) | RAB9ANPC1KDM4EALDH1A1GAA | |
| SCHEMBL28331079 | 0.79 | RAB9A (0.49) | RAB9APOLBDRD4DRD3NPC1 | |
| SCHEMBL27477674 | 0.78 | RAB9A (0.47) | RAB9APOLBDRD4DRD3NPC1 | |
| SCHEMBL31559974 | 0.78 | RAB9A (0.55) | RAB9APOLBDRD4DRD3NPC1 | |
| SCHEMBL18586692 | 0.78 | RAB9A (0.55) | RAB9APOLBDRD4DRD3NPC1 | |
| SCHEMBL20542272 | 0.78 | RAB9A (0.55) | RAB9APOLBDRD4DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100572381-C | Pyrazolonaphthyridine derivative | ASKA PHARM CO LTD (JP) | 2009-12-23 | — | — | CN | disclosed |