Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789789 | 0.89 | RAB9A (0.46) | RAB9APOLBALDH1A1SMN1; SMN2HPGDS | |
| SCHEMBL25336331 | 0.89 | MKNK2 (0.43) | RAB9APOLBALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6597674 | 0.86 | HPGDS (0.53) | ALDH1A1SMN1; SMN2HPGDSKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL1194018 | 0.85 | HPGDS (0.52) | ALDH1A1SMN1; SMN2HPGDSKDM4EHSD17B10 | |
| SCHEMBL28784637 | 0.85 | LTA4H (0.51) | RAB9APOLBALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL27768180 | 0.84 | RAB9A (0.52) | RAB9APOLBALDH1A1SMN1; SMN2DRD4 | |
| SCHEMBL20239625 | 0.82 | NR1H2 (0.49) | RAB9AALDH1A1SMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL8691392 | 0.82 | CA2 (0.54) | CDK2 | |
| SCHEMBL28775522 | 0.82 | HTR2C (0.45) | RAB9APOLB | |
| SCHEMBL25337392 | 0.82 | MAPT (0.51) | RAB9APOLBALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106604747-A | PRODUCTS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS COURSING WITH A COGNITION DEFICIT OR IMPAIRMENT, AND OF NEURODEGENERATIVE DISEASES | 基础应用医学研究基金会 | 2017-04-26 | — | — | CN | claimed |
| CN-110483492-B | Dipeptidyl peptidase I inhibitors | 阿斯利康(瑞典)有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-109232423-B | Method for preparing polysubstituted pyrazole by one-pot substituted alkyne and hydrazine or hydrazine substituent reaction | 江苏大学 | 2021-05-25 | — | — | CN | disclosed |
| CN-106103423-B | Pyrazine compounds | 阿斯利康(瑞典)有限公司 | 2019-12-06 | — | — | CN | disclosed |
| CN-109232423-A | The method that one kettle way replaces alkynes and hydrazine or hydrazine substituent reaction to prepare multi-substituted pyrazol | 江苏大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-106103423-A | Chemical compound | 阿斯利康(瑞典)有限公司 | 2016-11-09 | — | — | CN | disclosed |