Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 9/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58530 | 0.86 | PIK3CD (0.42) | PIK3CDRIPK1 | |
| SCHEMBL5172866 | 0.82 | PIK3CD (0.41) | PIK3CDRIPK1 | |
| SCHEMBL5076983 | 0.81 | PDE2A (0.47) | PDE2A | |
| SCHEMBL27747174 | 0.81 | RIPK1 (0.40) | PIK3CDRIPK1PDE2A | |
| SCHEMBL5141366 | 0.75 | PIK3CD (0.44) | PIK3CDPDE2A | |
| SCHEMBL19377773 | 0.73 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL5080198 | 0.72 | ACVRL1 (0.46) | PIK3CD | |
| SCHEMBL14488065 | 0.72 | PDE2A (0.45) | PIK3CDPDE2A | |
| SCHEMBL14488061 | 0.72 | PDE2A (0.45) | PIK3CDPDE2A | |
| SCHEMBL60090 | 0.69 | PIK3CD (0.42) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466710-B | Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER HEALTHCARE LLC | 2013-05-29 | — | — | CN | disclosed |
| CN-101466710-A | Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER HEALTHCARE LLC (US) | 2009-06-24 | — | — | CN | disclosed |