Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 5/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 12/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2131662 | 0.85 | AVPR2 (0.49) | PDCD1CD274AVPR2 | |
| SCHEMBL2129587 | 0.84 | PDCD1 (0.47) | PDCD1CD274AVPR2AVPR1A | |
| SCHEMBL27789716 | 0.82 | PDCD1 (0.44) | PDCD1CD274AVPR2 | |
| SCHEMBL27789677 | 0.81 | PDCD1 (0.38) | PDCD1CD274AVPR2AVPR1A | |
| SCHEMBL2705200 | 0.79 | AVPR2 (0.43) | PDCD1CD274AVPR2AVPR1AROCK2 | |
| SCHEMBL2129812 | 0.77 | SLC22A12 (0.46) | PDCD1CD274AVPR2AVPR1AROCK2 | |
| SCHEMBL1495958 | 0.77 | ALDH1A1 (0.50) | AVPR2AVPR1A | |
| SCHEMBL8556725 | 0.75 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL27789681 | 0.73 | PDCD1 (0.38) | PDCD1CD274AVPR2 | |
| SCHEMBL2704715 | 0.73 | AVPR2 (0.45) | PDCD1CD274AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563347-A | Vasopressin V1a antagonists | VANTIA LTD (GB) | 2009-10-21 | — | — | CN | disclosed |