Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495958 | 0.91 | ALDH1A1 (0.50) | AVPR2AVPR1ARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2705200 | 0.84 | AVPR2 (0.43) | AVPR2AVPR1ARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2129587 | 0.83 | PDCD1 (0.47) | AVPR2AVPR1ARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2129812 | 0.81 | SLC22A12 (0.46) | AVPR2AVPR1ARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6991859 | 0.80 | AVPR1A (0.72) | AVPR2AVPR1AOXTR | |
| SCHEMBL6995135 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1ARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8556854 | 0.78 | RAB9A (0.49) | AVPR2AVPR1ARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2616315 | 0.77 | ADORA1 (0.36) | RAB9ASMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL6994936 | 0.76 | AVPR2 (0.62) | AVPR2AVPR1AOXTR | |
| SCHEMBL7351134 | 0.76 | AVPR2 (0.59) | AVPR2AVPR1ARAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997047625-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |
| WO-1997047624-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |