Urea

Urea

SCHEMBL27768242

N#CC(Cl)(Cl)Cl.NC(N)=O

nearest known ligand 0.60

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
TSHR P16473 3/20 0.60
TDP1 Q9NUW8 2/20 0.40
LMNA P02545 1/20 0.40
OR51E2 Q9H255 1/20 0.40
MCL1 Q07820 1/20 0.36
TP53 P04637 1/20 0.32
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL22468088 0.80 ALDH1A1 (0.60) ALDH1A1TSHRTDP1
Bicarbonate SCHEMBL5161378 0.78 ALDH1A1 (0.56) ALDH1A1TSHRTP53
SCHEMBL100297 0.78
SCHEMBL2397283 0.75
Carbon Tetrachloride SCHEMBL28309316 0.74 ALDH1A1 (0.50) ALDH1A1TSHRTDP1LMNAOR51E2
SCHEMBL4158386 0.73 ALDH1A1 (0.90) ALDH1A1TSHRTDP1
SCHEMBL9683824 0.73
Hydrochloric Acid SCHEMBL4078190 0.73
SCHEMBL27750845 0.73
Urea SCHEMBL17075286 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102558118-B Method for preparing 4-methyl nadic anhydride BEIJING NUTRICHEM INTERNAT TRADE CO LTD 2014-06-25 CN disclosed
CN-103621582-A Drug for controlling bacterial leaf blight of rice, and production method of drug XIANGZHOU COUNTY SCIENCE TECHNOLOGY INFORMATION RES INST 2014-03-12 CN disclosed
CN-102558118-A Method for preparing 4-methyl nadic anhydride BEIJING NUTRICHEM INTERNAT TRADE CO LTD 2012-07-11 CN disclosed
CN-101626686-A 3-substituent-1, 2, 3-benzotriazinone compounds for improving glutaminic synaptic responses CORTEX PHARMA INC 2010-01-13 CN disclosed