Methane

Methane

SCHEMBL27768265

C.CC(=N)c1ccccn1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
KDM4E B2RXH2 3/20 0.55
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
LMNA P02545 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
KMT2A Q03164 4/20 0.45
GSK3B P49841 1/20 0.44
TOP2A P11388 1/20 0.42
RAB9A P51151 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
MAPT P10636 3/20 0.41
NPC1 O15118 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
GAA P10253 2/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6006624 0.98
Propane SCHEMBL27968122 0.91 ALDH1A1 (0.55) ALDH1A1KDM4ECES2CES1L3MBTL1
SCHEMBL27838743 0.88 ALDH1A1 (0.52) ALDH1A1KDM4ECES2CES1L3MBTL1
SCHEMBL13130702 0.79 ALDH1A1 (0.61) ALDH1A1KDM4ECES2CES1L3MBTL1
SCHEMBL11078493 0.78 CES2 (0.58) ALDH1A1KDM4ECES2CES1L3MBTL1
SCHEMBL1515056 0.78
SCHEMBL1921316 0.78 ALDH1A1 (0.67) ALDH1A1KDM4ECES2CES1L3MBTL1
Iodide SCHEMBL27882126 0.77 ALDH1A1 (0.59) ALDH1A1KDM4ECES2CES1L3MBTL1
SCHEMBL1930639 0.76
SCHEMBL947176 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106573947-B Metal complex MERCK PATENT GMBH (DE) 2019-11-01 CN disclosed
CN-109563115-A Method for separating enantiomeric mixtures of metal complexes 默克专利有限公司 2019-04-02 CN disclosed
CN-104870458-B Metal complex 默克专利有限公司 2019-02-15 CN disclosed
CN-105712986-B Metal complex with organic ligand and its purposes in OLED 默克专利有限公司 2019-01-01 CN disclosed
CN-104520308-B Metal complex 默克专利有限公司 2018-09-28 CN disclosed
CN-105531347-B Metal complex 默克专利有限公司 2018-09-11 CN disclosed
CN-104870459-B Metal complex 默克专利有限公司 2018-06-26 CN disclosed
CN-107849077-A Bridged electroluminescent metal complexes for use in electronic devices 默克专利有限公司 2018-03-27 CN disclosed
CN-104718219-B Metal complex 默克专利有限公司 2017-11-03 CN disclosed
CN-104428392-B Metal complexes 默克专利有限公司 2017-05-31 CN disclosed
CN-102812573-A Materials for organic electroluminescent devices MERCK PATENT GMBH 2012-12-05 CN disclosed
CN-102574882-A Metal complexes MERCK PATENT GMBH 2012-07-11 CN disclosed
CN-102317407-A Metal complexes containing azaborol ligands and electronic devices containing the same MERCK PATENT GMBH 2012-01-11 CN disclosed
CN-102282150-A Metal complexes 2011-12-14 CN disclosed
CN-102077380-A Electronic devices comprising metal complexes having isonitrile ligands MERCK PATENT GMBH 2011-05-25 CN disclosed
CN-102076812-A Complexes for use in optoelectronic components MERCK PATENT GMBH 2011-05-25 CN disclosed
CN-102076817-A Organic electroluminescence device MERCK PATENT GMBH 2011-05-25 CN disclosed
CN-102057014-A Electronic device comprising metal complexes MERCK PATENT GMBH 2011-05-11 CN disclosed
CN-101687889-A Luminescent metal complexes for organic electronic devices MERCK PATENT GMBH 2010-03-31 CN disclosed
CN-100582114-C Aromatic monomer-and conjugated polymer-metal complexes SUMITOMO CHEMICAL CO 2010-01-20 CN disclosed