Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL30455781 | 1.00 | FFAR3 (0.41) | FFAR3LCKFYNCYP2C19ALDH1A1 | |
| Acetic Acid SCHEMBL30455783 | 1.00 | FFAR3 (0.41) | FFAR3LCKFYNCYP2C19ALDH1A1 | |
| Acetic Acid SCHEMBL8401637 | 0.97 | FFAR3 (0.44) | FFAR3LCKFYNCYP2C19ALDH1A1 | |
| Acetone SCHEMBL9169110 | 0.91 | LMNA (0.38) | FFAR3CYP2C19ALDH1A1SMN1; SMN2USP2 | |
| Bicarbonate SCHEMBL28681892 | 0.88 | CYP2C19 (0.40) | FFAR3CYP2C19ALDH1A1SMN1; SMN2USP2 | |
| Bicarbonate SCHEMBL6243183 | 0.88 | CYP2C19 (0.40) | FFAR3CYP2C19ALDH1A1SMN1; SMN2USP2 | |
| Methacrylic Acid SCHEMBL6083326 | 0.85 | CYP2C19 (0.32) | CYP2C19ALDH1A1SMN1; SMN2USP2LMNA | |
| Methacrylic Acid SCHEMBL436556 | 0.85 | CYP2C19 (0.32) | CYP2C19ALDH1A1SMN1; SMN2USP2LMNA | |
| Methacrylic Acid SCHEMBL6081821 | 0.85 | CYP2C19 (0.32) | CYP2C19ALDH1A1SMN1; SMN2USP2LMNA | |
| Methacrylic Acid SCHEMBL1930431 | 0.85 | CYP2C19 (0.32) | CYP2C19ALDH1A1SMN1; SMN2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415572-B | Color material dispersion liquid, colored resin composition, color filter, liquid crystal display device, and light-emitting display device | 大日本印刷株式会社 | 2020-08-28 | — | — | CN | disclosed |
| CN-101490170-A | Curable resin composition and method for forming cured coating film | DAICEL CHEM (JP) | 2009-07-22 | — | — | CN | disclosed |