Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768228 | 0.96 | PTPN11 (0.45) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL10517750 | 0.83 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| Decoquinate SCHEMBL29373625 | 0.80 | DPP4 (0.46) | LMNANPC1RAB9AHSD17B10KDM4E | |
| Decoquinate SCHEMBL43853 | 0.80 | DPP4 (0.46) | LMNANPC1RAB9AHSD17B10KDM4E | |
| Decoquinate SCHEMBL14247781 | 0.78 | DPP4 (0.44) | LMNANPC1RAB9AHSD17B10KDM4E | |
| Decoquinate SCHEMBL14247780 | 0.77 | DPP4 (0.44) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| Decoquinate SCHEMBL15152849 | 0.76 | LMNA (0.47) | MAPTALDH1A1LMNAMAPK1NPC1 | |
| Decoquinate SCHEMBL10696854 | 0.76 | DPP4 (0.42) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL6202289 | 0.75 | DPP4 (0.60) | MAPTSMN1; SMN2TP53KMT2APOLB | |
| SCHEMBL22589588 | 0.74 | DPP4 (0.53) | MAPTSMN1; SMN2TP53KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101607937-A | Synthetic and the application of 6-alkoxyl group-7-phenyl-4-hydroxyl-3-quinoline carboxylic ester | UNIV SICHUAN (CN) | 2009-12-23 | — | — | CN | disclosed |