Decoquinate

Decoquinate

SCHEMBL43853

CCCCCCCCCCOc1cc2c(O)c(C(=O)OCC)cnc2cc1OCC

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.46
ESR1 P03372 2/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 1/20 0.41
HSD17B10 Q99714 1/20 0.41
AKR1C4 P17516 1/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
KDM4E B2RXH2 1/20 0.39
KDM4A O75164 1/20 0.39
KDM4C Q9H3R0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Decoquinate SCHEMBL29373625 1.00 DPP4 (0.46) DPP4ESR1NPC1LMNARAB9A
Decoquinate SCHEMBL14247781 0.98 DPP4 (0.44) DPP4ESR1NPC1LMNARAB9A
Decoquinate SCHEMBL14247780 0.97 DPP4 (0.44) DPP4ESR1NPC1LMNARAB9A
Decoquinate SCHEMBL10696854 0.95 DPP4 (0.42) DPP4ESR1NPC1LMNARAB9A
Decoquinate SCHEMBL15152849 0.89 LMNA (0.47) DPP4NPC1LMNARAB9AHSD17B10
SCHEMBL7071545 0.88 PTPN11 (0.45) HSD17B10
SCHEMBL28319922 0.86 DPP4 (0.61) DPP4LMNARAB9A
SCHEMBL27768228 0.84 PTPN11 (0.45) NPC1LMNARAB9AHSD17B10KDM4E
SCHEMBL29409636 0.83 DPP4 (0.53) DPP4
SCHEMBL22589588 0.83 DPP4 (0.53) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5704 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564571-B2 Compositions and methods for the treatment of equine protozoal myeloencephalitis GOING BIG TIME INC (US) 2026-03-03 US claimed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO claimed
WO-2025151713-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO claimed
US-20250222082-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS ARKEA BIO CORP (US) 2025-07-10 US claimed
WO-2025128700-A1 CELL-BASED VACCINES Arkea Bio Corp. (US) 2025-06-19 WO claimed
WO-2025085377-A1 USE OF ZOALENE IN LIVESTOCK ZOETIS SERVICES LLC (US) 2025-04-24 WO claimed
CN-119606968-A Composite preparation of embedded decoquinate and preparation method thereof 浙江汇能生物股份有限公司 2025-03-14 CN claimed
CN-119157887-A Does not contain ethanol or iso propanol calcipotriol composition 江苏知原药业股份有限公司 2024-12-20 CN claimed
CN-119015233-A Preparation method of decoquinate nano powder, product and application thereof 山东德州神牛药业有限公司 2024-11-26 CN claimed
CN-118724807-B Decoquinate hapten, antigen, antibody and preparation and application thereof 广州科技贸易职业学院 2024-11-15 CN claimed
WO-1994024886-A1 COMPOSITIONS FOR ADMINISTRATION TO ANIMALS WITH COCCIDIOSIS CULTOR LTD. (FI) 1994-11-10 WO claimed
US-5209866-A HETEROCYCLIC 1,2-DIFLUOROBENZENE DERIVATIVES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-05-11 US claimed
US-5200418-A Orally administering decoquinate to neonatal bovine exposed and susceptivle to infection by cryptosporidium oocysts THE OHIO STATE UNIVERSITY (US) 1993-04-06 US claimed
EP-0107759-B1 CYCLOHEXANE DERIVATIVES AND THEIR USE AS COMPONENTS FOR LIQUID CRYSTALS MERCK PATENT GmbH (DE) 1992-12-16 EP claimed
US-5043093-A Liquid crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-08-27 US claimed
EP-0227717-B1 NITROGEN-CONTAINING HETEROCYCLIC ESTERS MERCK PATENT GmbH (DE) 1990-04-25 EP claimed
US-4882082-A PYRIMIDINE DERIVATIVE LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-11-21 US claimed
US-4820839-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-04-11 US claimed
US-4195089-A Synergistic composition for malaria BURROUGHS WELLCOME CO. (US) 1980-03-25 US claimed
US-4085141-A Process for the preparation of anilines meta-substituted by chlorine BAYER AKTIENGESELLSCHAFT (DT) 1978-04-18 US claimed