Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14631107 | 0.85 | KMT2A (0.41) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28477897 | 0.84 | KMT2A (0.62) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27560790 | 0.79 | KMT2A (0.67) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11874927 | 0.79 | CA12 (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL9596419 | 0.77 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3286100 | 0.77 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3499430 | 0.76 | SERPINE1 (0.43) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8349997 | 0.76 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3968836 | 0.75 | NPSR1 (0.58) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6990472 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563322-A | 1H-indole-2-carboxylic acid derivatives useful as PPAR modulators | SMITHKLINE BEECHAM CORPORAITON (US) | 2009-10-21 | — | — | CN | disclosed |