Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768338 | 0.85 | KMT2A (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8091604 | 0.82 | MEN1 (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4425234 | 0.78 | SLC6A2 (0.37) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL532533 | 0.76 | KDM4E (0.46) | KMT2AMEN1ALDH1A1KDM4EESR1 | |
| SCHEMBL3485687 | 0.75 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1KDM4ESLC6A4 | |
| Hydrochloric Acid SCHEMBL9785714 | 0.74 | ESR1 (0.58) | KMT2AMEN1ALDH1A1KDM4EESR1 | |
| Hydrochloric Acid SCHEMBL27714396 | 0.74 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1KDM4ESLC6A4 | |
| SCHEMBL6621005 | 0.72 | SLC6A4 (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3839948 | 0.72 | KMT2A (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7603869 | 0.72 | SLC6A2 (0.61) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547655-A2 | ARYLSULFONAMIDE CCR3 ANTAGONISTS | Axikin Pharmaceuticals, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |