Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157795 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL2346744 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL4343028 | 0.83 | GAA (0.64) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL29369014 | 0.82 | CA1 (0.58) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL14484919 | 0.81 | LMNA (0.68) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL11228520 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL4352949 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL25304013 | 0.77 | TP53 (0.48) | ALDH1A1MAPTKMT2AMEN1TP53 | |
| SCHEMBL12481671 | 0.76 | ALDH1A1 (0.66) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL17479351 | 0.76 | KMT2A (0.56) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563322-A | 1H-indole-2-carboxylic acid derivatives useful as PPAR modulators | SMITHKLINE BEECHAM CORPORAITON (US) | 2009-10-21 | — | — | CN | disclosed |