Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28784684 | 0.77 | MAPT (0.48) | GAAMAPTALDH1A1 | |
| SCHEMBL27790180 | 0.76 | GAA (0.57) | GAAMAPT | |
| SCHEMBL27768464 | 0.75 | MAPT (0.53) | GAAMAPTTDP1 | |
| SCHEMBL27768438 | 0.75 | MAPT (0.53) | GAAMAPT | |
| SCHEMBL13241463 | 0.75 | GAA (0.56) | GAAMAPTALDH1A1 | |
| SCHEMBL4999605 | 0.75 | GAA (0.56) | GAAMAPT | |
| 1,2-Dimethoxybenzene SCHEMBL27572044 | 0.72 | GAA (0.53) | GAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL926564 | 0.72 | DRD2 (0.52) | GAAMAPTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7660514 | 0.72 | DRD2 (0.52) | GAAMAPTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL27665063 | 0.72 | GAA (0.51) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |