Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199879 | 0.79 | MAPT (0.40) | MAPTGAAKDM4EHIF1AKEAP1 | |
| SCHEMBL12629105 | 0.79 | MAPT (0.47) | MAPTGAAKDM4EHIF1APOLB | |
| SCHEMBL27768522 | 0.78 | MAPT (0.49) | MAPTGAAKDM4EHIF1AALDH1A1 | |
| SCHEMBL27768409 | 0.77 | GAA (0.54) | MAPTGAAALDH1A1 | |
| SCHEMBL13229755 | 0.76 | S1PR5 (0.53) | MAPTGAAKDM4EHIF1AFFAR1 | |
| SCHEMBL27768438 | 0.76 | MAPT (0.53) | MAPTGAAKDM4EHIF1A | |
| SCHEMBL13228878 | 0.75 | MAPT (0.49) | MAPTGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL27768482 | 0.75 | S1PR5 (0.51) | MAPTGAAFFAR1 | |
| SCHEMBL27790051 | 0.74 | S1PR5 (0.47) | MAPTGAAFFAR1 | |
| SCHEMBL15095006 | 0.73 | GAA (0.41) | MAPTGAAKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |