Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 12/20 | 0.71 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA4 | P22748 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69876 | 0.89 | ESRRA (0.62) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL28801446 | 0.87 | ESRRA (0.60) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL23153549 | 0.85 | ESRRA (0.59) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL19691104 | 0.85 | ESRRA (0.63) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL23889183 | 0.85 | ESRRA (0.59) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL28814811 | 0.84 | ESRRA (1.00) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27768480 | 0.83 | ESRRA (0.53) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27983565 | 0.83 | ESRRA (0.77) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27983984 | 0.81 | CA1 (0.66) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL24380262 | 0.81 | ESRRA (0.55) | ESRRACA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104119285-A | Compound used as estrogen-related receptor regulator and application of compound | GUANGZHOU INST BIOMED & HEALTH | 2014-10-29 | — | — | CN | claimed |
| CN-104119285-A | Compound used as estrogen-related receptor regulator and application of compound | GUANGZHOU INST BIOMED & HEALTH | 2014-10-29 | — | — | CN | disclosed |
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |