Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 5/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69876 | 0.98 | ESRRA (0.62) | ESRRAP2RX7NOTUML3MBTL1CA1 | |
| SCHEMBL31734379 | 0.89 | HPGDS (0.57) | ESRRAP2RX7NOTUML3MBTL1CA1 | |
| SCHEMBL1749529 | 0.88 | OGT (0.53) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27768462 | 0.87 | ESRRA (0.71) | ESRRAP2RX7NOTUML3MBTL1CA1 | |
| SCHEMBL23889183 | 0.84 | ESRRA (0.59) | ESRRAP2RX7NOTUML3MBTL1CA1 | |
| SCHEMBL19691104 | 0.84 | ESRRA (0.63) | ESRRAP2RX7NOTUML3MBTL1CA1 | |
| SCHEMBL27877288 | 0.84 | ESRRA (0.57) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL23153549 | 0.84 | ESRRA (0.59) | ESRRAP2RX7NOTUML3MBTL1CA1 | |
| SCHEMBL4708257 | 0.84 | MAOA (0.49) | ESRRANOTUML3MBTL1CA1CA2 | |
| SCHEMBL28039291 | 0.83 | ESRRA (0.49) | ESRRAP2RX7NOTUML3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985439-B9 | IAP BIR domain binding compounds | 制药科学股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-102985439-B | IAP BIR domain binding compounds | 制药科学股份有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-102985439-A | IAP BIR domain binding compounds | AEGERA THERAPEUTICS INC | 2013-03-20 | — | — | CN | disclosed |