Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 8/20 | 0.53 |
| ▸ | CA1 | P00915 | 9/20 | 0.51 |
| ▸ | CA2 | P00918 | 9/20 | 0.51 |
| ▸ | CA4 | P22748 | 9/20 | 0.51 |
| ▸ | CA9 | Q16790 | 9/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708257 | 0.87 | MAOA (0.49) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL30808842 | 0.86 | MAOA (0.51) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27768462 | 0.83 | ESRRA (0.71) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL12571599 | 0.82 | CA1 (0.64) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27983984 | 0.80 | CA1 (0.66) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27768446 | 0.80 | ESRRA (0.51) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27983544 | 0.76 | ESRRA (0.77) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27889079 | 0.76 | CA1 (0.41) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL27983551 | 0.73 | NOTUM (0.61) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL69876 | 0.72 | ESRRA (0.62) | ESRRACA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |