Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27790053 | 0.94 | DRD2 (0.47) | MAPTGAADRD2DRD3HTR2B | |
| SCHEMBL7669208 | 0.89 | GAA (0.48) | MAPTGAADRD2DRD3HTR2A | |
| SCHEMBL13229755 | 0.85 | S1PR5 (0.53) | MAPTGAADRD2DRD3S1PR5 | |
| SCHEMBL27768482 | 0.84 | S1PR5 (0.51) | MAPTGAADRD2DRD3S1PR5 | |
| SCHEMBL27790051 | 0.83 | S1PR5 (0.47) | MAPTGAADRD2DRD3S1PR5 | |
| SCHEMBL7660514 | 0.82 | DRD2 (0.52) | MAPTGAADRD2DRD3ALDH1A1 | |
| SCHEMBL926564 | 0.82 | DRD2 (0.52) | MAPTGAADRD2DRD3ALDH1A1 | |
| SCHEMBL12628272 | 0.82 | BRD4 (0.49) | MAPTGAADRD2DRD3ALDH1A1 | |
| SCHEMBL12596308 | 0.81 | DRD2 (0.48) | MAPTGAADRD2DRD3ALDH1A1 | |
| 1,2-Dimethoxybenzene SCHEMBL27572044 | 0.80 | GAA (0.53) | MAPTGAADRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |