Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669210 | 1.00 | GAA (0.48) | GAAMAPTDRD2DRD3GLA | |
| Benzene SCHEMBL27768484 | 0.89 | MAPT (0.46) | GAAMAPTDRD2DRD3HTR2A | |
| Benzene SCHEMBL27790053 | 0.88 | DRD2 (0.47) | GAAMAPTDRD2DRD3HTR2B | |
| SCHEMBL7037275 | 0.86 | DRD2 (0.45) | GAAMAPTDRD2DRD3GLA | |
| SCHEMBL926564 | 0.84 | DRD2 (0.52) | GAAMAPTDRD2DRD3L3MBTL1 | |
| SCHEMBL7660514 | 0.84 | DRD2 (0.52) | GAAMAPTDRD2DRD3L3MBTL1 | |
| 1,2-Dimethoxybenzene SCHEMBL27572044 | 0.82 | GAA (0.53) | GAAMAPTDRD2DRD3MTNR1A | |
| SCHEMBL27768482 | 0.81 | S1PR5 (0.51) | GAAMAPTDRD2DRD3HPGD | |
| SCHEMBL7044461 | 0.80 | GAA (0.46) | GAAMAPTDRD2DRD3L3MBTL1 | |
| SCHEMBL27790051 | 0.80 | S1PR5 (0.47) | GAAMAPTDRD2DRD3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403561-B1 | DISORDERS ASSOCIATED WITH THE INACTIVATION OR EXCESSIVE DEGRADATION OF CHOLECYSTOKININ; INHIBITING THE ENZYMATIC HYDROLYSIS OF CHOLECYSTOKININ 1-(2(S)-AMINOBUTYRYL)-2(S)-INDOLINECARBOXYLIC ACID | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-06-11 | — | — | US | disclosed |