Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.36 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414195 | 0.83 | YTHDF2 (0.83) | YTHDF2DAOCSF1RALDH1A1LMNA | |
| SCHEMBL27831184 | 0.74 | ALDH1A1 (0.41) | YTHDF2ALDH1A1LMNAPOLBNR1I2 | |
| SCHEMBL9414252 | 0.74 | YTHDF2 (1.00) | YTHDF2DAOALDH1A1LMNAPOLB | |
| SCHEMBL28878319 | 0.68 | ADORA2A (0.38) | ALDH1A1LMNAPOLBADORA2AADORA2B | |
| SCHEMBL9420362 | 0.67 | ALDH1A1 (0.45) | YTHDF2DAOALDH1A1LMNAPOLB | |
| SCHEMBL20075886 | 0.66 | NPY5R (0.42) | YTHDF2DAOCSF1RPOLBNR1I2 | |
| SCHEMBL19583314 | 0.66 | YTHDF2 (0.48) | YTHDF2DAOCSF1RALDH1A1LMNA | |
| SCHEMBL19583294 | 0.66 | CSF1R (0.39) | YTHDF2DAOCSF1RALDH1A1LMNA | |
| SCHEMBL13885282 | 0.66 | PARP1 (0.41) | YTHDF2DAOCSF1RALDH1A1YTHDF3 | |
| SCHEMBL28154327 | 0.66 | ADORA2A (0.37) | ALDH1A1LMNAPOLBADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101475536-A | Polysubstituted S-DACO derivative, synthesizing method and use thereof | UNIV YUNNAN (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-101475535-A | Polysubstituted N-DACO derivative, synthesizing method and use thereof | UNIV YUNNAN (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-110483487-A | A kind of 2- thiomethylpyrazole pyrimidinones, preparation method, pharmaceutical composition and application | UNIV YUNNAN | 2019-11-22 | — | — | CN | disclosed |
| CN-101475536-A | Polysubstituted S-DACO derivative, synthesizing method and use thereof | UNIV YUNNAN (CN) | 2009-07-08 | — | — | CN | disclosed |
| CN-101475535-A | Polysubstituted N-DACO derivative, synthesizing method and use thereof | UNIV YUNNAN (CN) | 2009-07-08 | — | — | CN | disclosed |