Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 15/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768447 | 0.93 | S1PR3 (0.48) | S1PR3PLA2G2A | |
| SCHEMBL27905705 | 0.92 | S1PR3 (0.46) | S1PR3PLA2G2AMAPTALDH1A1GAA | |
| SCHEMBL27789967 | 0.91 | S1PR3 (0.53) | S1PR3PLA2G2AMAPTALDH1A1GAA | |
| SCHEMBL27768470 | 0.87 | S1PR3 (0.41) | S1PR3PLA2G2AMAPTALDH1A1GAA | |
| SCHEMBL27790054 | 0.85 | PLA2G2A (0.61) | PLA2G2AMAPTALDH1A1GAAPKM | |
| SCHEMBL27768481 | 0.84 | S1PR3 (0.48) | S1PR3PLA2G2AMAPTALDH1A1GAA | |
| SCHEMBL27768594 | 0.83 | S1PR3 (0.46) | S1PR3PLA2G2AMAPTALDH1A1GAA | |
| SCHEMBL4664582 | 0.83 | PLA2G2A (0.54) | S1PR3PLA2G2AMAPTALDH1A1GAA | |
| SCHEMBL2010316 | 0.81 | S1PR3 (0.65) | S1PR3PLA2G2AMAPTALDH1A1GAA | |
| SCHEMBL2001945 | 0.79 | PLA2G2A (0.60) | S1PR3PLA2G2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |