Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 3/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789967 | 0.93 | S1PR3 (0.53) | S1PR3ABCB11MAPTGAAPKM | |
| SCHEMBL27768447 | 0.91 | S1PR3 (0.48) | S1PR3ABCB11PLA2G2A | |
| SCHEMBL27768594 | 0.90 | S1PR3 (0.46) | S1PR3ABCB11MAPTGAAPKM | |
| SCHEMBL27789959 | 0.84 | L3MBTL1 (0.44) | S1PR3ABCB11MAPTGAAPKM | |
| SCHEMBL27768492 | 0.84 | S1PR3 (0.53) | S1PR3MAPTGAAPKMALDH1A1 | |
| SCHEMBL27905705 | 0.81 | S1PR3 (0.46) | S1PR3MAPTGAAPKMALDH1A1 | |
| SCHEMBL27789996 | 0.79 | PLA2G2A (0.40) | S1PR3MAPTGAAALDH1A1KDM4E | |
| SCHEMBL27790041 | 0.79 | S1PR3 (0.37) | S1PR3MAPTGAAPKMALDH1A1 | |
| SCHEMBL2003321 | 0.79 | S1PR3 (0.60) | S1PR3ABCB11MAPTGAAPKM | |
| SCHEMBL6025561 | 0.79 | MAPT (0.54) | ABCB11MAPTGAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |