Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843818 | 0.89 | TP53 (0.44) | TP53KMOAKR1B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27768523 | 0.83 | CASP1 (0.38) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL27768467 | 0.82 | MKNK1 (0.47) | KMOALDH1A1 | |
| SCHEMBL23930619 | 0.81 | GSK3B (0.46) | TP53KMOAKR1B1CYP11B1CYP11B2 | |
| SCHEMBL8880792 | 0.81 | ADORA1 (0.48) | AKR1B1CYP11B1CYP11B2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8879951 | 0.79 | SMN1; SMN2 (0.49) | AKR1B1CYP11B1CYP11B2SMN1; SMN2ALDH1A1 | |
| SCHEMBL23930520 | 0.76 | CLK1 (0.41) | CYP11B1CYP11B2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15083062 | 0.74 | MAPK14 (0.43) | ALDH1A1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL2722584 | 0.74 | MKNK1 (0.58) | KMOALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5153375 | 0.74 | MEN1 (0.42) | TP53CYP11B1CYP11B2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |