Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972611 | 0.82 | CA1 (0.50) | KDM4EALDH1A1POLBALOX15KMT2A | |
| SCHEMBL9568684 | 0.79 | KMT2A (0.47) | KDM4EALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL18003902 | 0.79 | MGAM (0.55) | KDM4EALDH1A1HSD17B10POLBKMT2A | |
| SCHEMBL27768804 | 0.79 | KDM4E (0.58) | KDM4EHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL10561406 | 0.79 | KDM4E (0.71) | KDM4EHPGDALDH1A1HSD17B10POLB | |
| SCHEMBL212851 | 0.74 | KDM4E (0.61) | KDM4EHPGDALDH1A1HSD17B10POLB | |
| SCHEMBL4467860 | 0.71 | KDM4E (0.61) | KDM4EHPGDALDH1A1HSD17B10POLB | |
| SCHEMBL369633 | 0.69 | KDM4E (1.00) | KDM4EHPGDALDH1A1HSD17B10POLB | |
| SCHEMBL969939 | 0.69 | KDM4E (0.59) | KDM4EHPGDALDH1A1HSD17B10POLB | |
| SCHEMBL3962310 | 0.69 | KDM4E (0.59) | KDM4EHPGDALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |