Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424931 | 0.82 | KDM4E (0.75) | KDM4ESMN1; SMN2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL27768554 | 0.79 | KDM4E (0.53) | KDM4ESMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL212959 | 0.78 | RAB9A (0.60) | KDM4ESMN1; SMN2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL12278703 | 0.75 | KDM4E (0.66) | KDM4ESMN1; SMN2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL255577 | 0.75 | KDM4E (0.66) | KDM4ESMN1; SMN2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL30803985 | 0.75 | KDM4E (0.66) | KDM4ESMN1; SMN2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL1680233 | 0.75 | HSD17B10 (0.55) | KDM4ESMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27790186 | 0.75 | CYP2A6 (0.58) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL27817490 | 0.74 | KDM4E (0.51) | KDM4ESMN1; SMN2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL970073 | 0.74 | KDM4E (0.64) | KDM4ESMN1; SMN2CYP2A6CYP3A4CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |