Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | MGAM | O43451 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | SI | P14410 | 4/20 | 0.62 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561406 | 0.84 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL45441 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL28851907 | 0.80 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL21408723 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL29845591 | 0.79 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| Hydrochloric Acid SCHEMBL3691525 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL23918236 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL6902047 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL1143313 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL1143676 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255729-A | Method for synthesizing 2-amino-5-substituted-1, 3, 4-thiadiazole | 陕西科技大学 | 2024-06-28 | — | — | CN | claimed |
| CN-101691662-B | Carbon steel pickling corrosion inhibitor and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2011-01-12 | — | — | CN | claimed |
| US-20100234377-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2010-09-16 | — | — | US | claimed |
| CN-101691662-A | Carbon steel pickling corrosion inhibitor and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2010-04-07 | — | — | CN | claimed |
| US-12540274-B2 | Electrochromic composition and electrochromic device | TAI YING OPTRONICS CO., LTD. (TW) | 2026-02-03 | — | — | US | disclosed |
| CN-121342819-A | 5-Chloro-3-methyl-1-phenyl-4-pyrazol-formald 2-amino-5- (4-pyridyl) -1,3, 4-thiadiazole compound, and preparation method and application thereof | 淮阴师范学院 | 2026-01-16 | — | — | CN | disclosed |
| CN-121342819-A | 5-Chloro-3-methyl-1-phenyl-4-pyrazol-formald 2-amino-5- (4-pyridyl) -1,3, 4-thiadiazole compound, and preparation method and application thereof | 淮阴师范学院 | 2026-01-16 | — | — | CN | disclosed |
| CN-120077028-A | Thiadiazole derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| US-20250136861-A1 | ELECTROCHROMIC COMPOSITION AND ELECTROCHROMIC DEVICE | TAI YING OPTRONICS CO., LTD. (TW) | 2025-05-01 | — | — | US | disclosed |
| CN-119371374-A | Green synthesis method of 2-amino-5-aryl-1, 3, 4-thiadiazole | 陕西科技大学 | 2025-01-28 | — | — | CN | disclosed |
| US-12139635-B2 | Coatings for waterproofing electronic components | HENKEL AG & CO. KGAA (DE) | 2024-11-12 | — | — | US | disclosed |
| US-20240270735-A1 | CDK19-Selective Inhibitors, and Methods of Use Thereof | CHAN ZUCKERBERG BIOHUB, INC. | 2024-08-15 | — | — | US | disclosed |
| EP-1558607-A1 | COMPOSITIONS USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES | Vertex Pharmaceuticals Incorporated (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2005005435-A1 | SPIRO ′1-AZABICYCLO ′2.2.2!OCTAN-3,5′-OXAZOLIDIN -2′-ONE! DERIVATIVES WITH AFFINITY TO THE ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR | ASTRAZENECA AB (SE) | 2005-01-20 | — | — | WO | disclosed |
| US-20040122016-A1 | Compositions useful as inhibitors of rock and other protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2004-06-24 | — | — | US | disclosed |
| WO-2004041813-A1 | COMPOSITIONS USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2004-05-21 | — | — | WO | disclosed |
| EP-1054876-A1 | 1,3,4-THIADIAZOLES DERIVATIVES AS KYN-OH INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999028309-A1 | 1,3,4-THIADIAZOLES DERIVATIVES AS KYN-OH INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |
| US-4271166-A | N-(1,3,4-Thiadiazol-2-yl)benzamides | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4141984-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540274-B2 | Electrochromic composition and electrochromic device | CHRM1, CHRM2, TYR | KDM4E 404/4885ALDH1A1 1132/4885HSD17B10 3023/4885 |
| US-20240270735-A1 | CDK19-Selective Inhibitors, and Methods of Use Thereof | CDK19, CDK9, CDK1 | KDM4E 904/4885ALDH1A1 4629/4885HSD17B10 1436/4885 |
| US-20040122016-A1 | Compositions useful as inhibitors of rock and other protein kinases | ROCK1, ROCK2, PRKCH | KDM4E 2286/4885ALDH1A1 4771/4885HSD17B10 3750/4885 |
| US-20100234377-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | HPGDS, PTGDR, PTGIS | KDM4E 3580/4885ALDH1A1 614/4885HSD17B10 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.