Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552987 | 0.88 | ALDH1A1 (0.50) | — | |
| SCHEMBL1553949 | 0.84 | RAB9A (0.53) | MAPK1ABL1AURKBPIM1 | |
| SCHEMBL1552950 | 0.80 | MAPK1 (0.44) | MAPK1ABL1AURKBPIM1PIK3CA | |
| SCHEMBL1553754 | 0.78 | MAPK1 (0.42) | MAPK1ABL1AURKBPIM1PIK3CA | |
| SCHEMBL12708255 | 0.78 | ABL1 (0.42) | MAPK1ABL1AURKBPIM1 | |
| SCHEMBL1553109 | 0.78 | MAPK1 (0.42) | MAPK1ABL1AURKBPIM1PIK3CA | |
| SCHEMBL3211458 | 0.78 | ABL1 (0.42) | MAPK1ABL1AURKBPIM1 | |
| SCHEMBL12707834 | 0.76 | ABL1 (0.41) | MAPK1ABL1AURKBPIM1 | |
| SCHEMBL12708361 | 0.75 | ABL1 (0.40) | MAPK1ABL1AURKBPIM1 | |
| SCHEMBL1553254 | 0.75 | ABL1 (0.42) | MAPK1ABL1AURKBPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101627038-A | Antibacterial polycyclic urea compounds | ASTRAZENECA AB | 2010-01-13 | — | — | CN | disclosed |