Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683862 | 0.91 | ALDH1A1 (0.68) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL1683742 | 0.89 | ALDH1A1 (0.60) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL287420 | 0.89 | ALDH1A1 (0.74) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL2866244 | 0.85 | HDAC1 (0.71) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL893099 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL6706804 | 0.85 | ALDH1A1 (0.70) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL1683628 | 0.84 | ALDH1A1 (0.59) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL27768521 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL25062869 | 0.82 | ALDH1A1 (0.66) | ALDH1A1HDAC1HDAC8HDAC6PDE4B | |
| SCHEMBL19382473 | 0.81 | HDAC1 (0.74) | ALDH1A1HDAC1HDAC8HDAC6PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |