SCHEMBL6706804

SCHEMBL6706804

CC(=O)c1coc(-c2ccccc2)n1

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.70
HDAC1 Q13547 9/20 0.66
HDAC8 Q9BY41 9/20 0.66
HDAC6 Q9UBN7 9/20 0.66
PDE4B Q07343 3/20 0.56
DAGLA Q9Y4D2 1/20 0.49
HSD17B1 P14061 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287420 0.85 ALDH1A1 (0.74) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL27768646 0.85 ALDH1A1 (0.74) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL2222487 0.83 HDAC1 (0.68) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL10029551 0.82 HDAC1 (0.51) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL2866244 0.82 HDAC1 (0.71) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL893099 0.82 ALDH1A1 (1.00) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL167905 0.81 HDAC1 (0.74) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL6386434 0.81 HDAC1 (0.65) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL1683862 0.81 ALDH1A1 (0.68) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL25062869 0.79 ALDH1A1 (0.66) ALDH1A1HDAC1HDAC8HDAC6PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768164-A Pharmaceutical compounds for treating complement-mediated disorders 阿雷克森制药公司 2025-04-04 CN disclosed
CN-116234800-A Copper complexes for the treatment of neurodegenerative disorders ALS治疗发展学会 2023-06-06 CN disclosed
US-20230054997-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS ALS THERAPY DEVELOPMENT INSTITUTE, 2023-02-23 US disclosed
US-6835846-B2 The present invention provides an aliphatic compound represented by the following formula (I) or pharmacologically acceptable salts thereof: the aliphatic compound being an optical isomer of the (2R,3S,2'S) configuration when the MARUHA CORPORATION (JP) 2004-12-28 US disclosed
US-20040014816-A1 Novel aliphatic compounds, process for their preparation and their usage MARUHA NICHIRO SEAFOODS, INC. (JP) 2004-01-22 US disclosed
EP-1325904-A1 NOVEL ALIPHATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USAGE Maruha Corporation (JP) 2003-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014816-A1 Novel aliphatic compounds, process for their preparation and their usage CPT1B, ACSS2, CERS2 ALDH1A1 139/4885HDAC1 1109/4885HDAC8 2170/4885
US-20230054997-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS SOD1, SMN1; SMN2, CLN6 ALDH1A1 1721/4885HDAC1 2333/4885HDAC8 2791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.