Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484489 | 0.81 | MEN1 (0.53) | MEN1KMT2AGAAPKMPDE7A | |
| SCHEMBL11771697 | 0.81 | PDE7A (0.59) | MEN1KMT2AGAAPKMPDE7A | |
| SCHEMBL10784186 | 0.81 | MEN1 (0.71) | MEN1KMT2AGAAPKMPDE7A | |
| SCHEMBL27887553 | 0.80 | MEN1 (0.56) | MEN1KMT2AGAAPKMPDE7A | |
| SCHEMBL3304697 | 0.79 | TDP1 (0.56) | MEN1KMT2AGAAPKMALDH1A1 | |
| SCHEMBL3484189 | 0.78 | TDP1 (0.64) | MEN1KMT2AGAAPKMPDE7A | |
| SCHEMBL3509441 | 0.77 | PDE7A (0.68) | MEN1KMT2AGAAPKMPDE7A | |
| SCHEMBL4697145 | 0.76 | KMT2A (0.54) | MEN1KMT2AGAAPKMPDE7A | |
| SCHEMBL11757479 | 0.76 | PDE7A (0.71) | MEN1KMT2AGAAPKMPDE7A | |
| SCHEMBL10690832 | 0.76 | ESRRA (0.47) | MEN1KMT2AGAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611041-A | Condensed heterocyclic compouds | TAKEDA PHARMACEUTICAL (JP) | 2009-12-23 | — | — | CN | disclosed |