Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30098850 | 0.84 | HPGD (0.63) | KMT2AMEN1PDE7AGAAPKM | |
| SCHEMBL22069578 | 0.84 | HPGD (0.63) | KMT2AMEN1PDE7AGAAPKM | |
| SCHEMBL10786123 | 0.82 | ALDH1A1 (0.50) | KMT2AMEN1PDE7AGAAPKM | |
| SCHEMBL11511746 | 0.82 | PDE7A (0.71) | KMT2AMEN1PDE7AGAAPKM | |
| SCHEMBL8740792 | 0.81 | HPGD (0.51) | KMT2AMEN1MAPTLMNATDP1 | |
| SCHEMBL13265729 | 0.80 | MAPT (0.62) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL641133 | 0.80 | HPGD (0.62) | GAAMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4029870 | 0.80 | PDE7A (0.73) | KMT2AMEN1PDE7AGAAPKM | |
| SCHEMBL14399017 | 0.80 | CTSV (0.53) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL17820180 | 0.80 | TBXA2R (0.55) | KMT2AMEN1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987037-A2 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007097470-A2 | FUSED NITROGEN- COMPRISING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-30 | — | — | WO | disclosed |