Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304697 | 0.87 | TDP1 (0.56) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10685127 | 0.83 | MEN1 (0.47) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10686059 | 0.82 | MEN1 (0.59) | KMT2AMEN1TDP1TTRPPOX | |
| Bifenox SCHEMBL11497295 | 0.77 | TDP1 (0.78) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL11334611 | 0.76 | EPAS1 (0.47) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL27768781 | 0.76 | MEN1 (0.55) | KMT2AMEN1TDP1TTRPPOX | |
| Ioxynil SCHEMBL10755216 | 0.76 | TDP1 (0.44) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL9852601 | 0.74 | TDP1 (0.54) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10690824 | 0.73 | TDP1 (0.78) | ESRRAKMT2AMEN1TDP1TTR | |
| SCHEMBL11354108 | 0.73 | MEN1 (0.56) | KMT2AMEN1TDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743703-A | Herbicidal 4-fluoroalkyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1988-05-10 | — | — | US | disclosed |