Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747673 | 0.90 | DRD4 (0.53) | SMOMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL4395226 | 0.88 | MAPT (0.67) | SMOMAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL4245787 | 0.88 | MAPT (0.67) | SMOMAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL4249859 | 0.86 | SLC6A4 (0.51) | MAPTLMNAALDH1A1DRD4DRD2 | |
| SCHEMBL4254360 | 0.85 | HTR7 (0.56) | SMOMAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL4253037 | 0.84 | MAPT (0.60) | MAPTLMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL4243305 | 0.83 | MAPT (0.48) | SMOMAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL4391668 | 0.81 | MAPT (0.54) | MAPTLMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL4254706 | 0.81 | MAPK1 (0.67) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4395117 | 0.81 | SLC6A2 (0.50) | MAPTLMNAL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490010-A | Compounds and compositions as ITPKB inhibitors | IRM LLC (VG) | 2009-07-22 | — | — | CN | disclosed |