Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768787 | 0.90 | SMO (0.60) | DRD4KDM4EALDH1A1SMN1; SMN2GFER | |
| SCHEMBL15938281 | 0.80 | HTR7 (0.73) | DRD4KDM4EALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL29764262 | 0.80 | HTR7 (0.73) | DRD4KDM4EALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL4250371 | 0.80 | HTR7 (0.65) | DRD4KDM4EALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL12204385 | 0.79 | MEN1 (0.60) | DRD4KDM4EALDH1A1GFERDRD2 | |
| SCHEMBL18409588 | 0.78 | DRD4 (0.66) | DRD4KDM4EALDH1A1SMN1; SMN2GFER | |
| SCHEMBL4245787 | 0.78 | MAPT (0.67) | DRD4KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4395226 | 0.78 | MAPT (0.67) | DRD4KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27395911 | 0.77 | DRD4 (0.55) | DRD4KDM4EALDH1A1SMN1; SMN2GFER | |
| SCHEMBL4251913 | 0.77 | HTR7 (0.67) | DRD4KDM4EALDH1A1SMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490010-A | Compounds and compositions as ITPKB inhibitors | IRM LLC (VG) | 2009-07-22 | — | — | CN | disclosed |