Tert-Butyl Formate

Tert-Butyl Formate

SCHEMBL27768808

C=CCO[C@H]1CCCNC1.CC(C)(C)OC=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRM3 P20309 1/20 0.35
CHRNA4 P43681 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14369096 0.84 CHRNB2 (0.41) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL6665422 0.84 CHRNB2 (0.41) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL1071308 0.84 CHRNB2 (0.41) CHRM2CHRM1CHRNB2CHRM3CHRNA4
Hydrochloric Acid SCHEMBL4432748 0.82 CHRNB2 (0.40) CHRM2CHRM1CHRNB2CHRM3CHRNA4
Hydrochloric Acid SCHEMBL4433636 0.82 CHRNB2 (0.40) CHRM2CHRM1CHRNB2CHRM3CHRNA4
Hydrochloric Acid SCHEMBL31511527 0.82 CHRNB2 (0.40) CHRM2CHRM1CHRNB2CHRM3CHRNA4
Trifluoroacetic Acid SCHEMBL27751161 0.77 SLC6A1 (0.36) CHRM2CHRM1CHRNB2CHRM3CHRNA4
Tert-Butyl Formate SCHEMBL27996949 0.76 TDP1 (0.41) CHRM2CHRM1CHRM3TDP1
Tert-Butyl Formate SCHEMBL27996950 0.76 TDP1 (0.41) CHRM2CHRM1CHRM3TDP1
Tert-Butyl Formate SCHEMBL27804927 0.75 TDP1 (0.37) CHRNB2CHRNA4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101611039-A HCV NS3 protease inhibitors MERCK & CO INC (US) 2009-12-23 CN disclosed