Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 3/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090799 | 0.92 | PTGDR2 (0.42) | MEN1KMT2APTGDR2HTR6KCNH2 | |
| SCHEMBL3094217 | 0.84 | MTNR1A (0.47) | PTGDR2HTR6KCNH2ABCC9ABCC8 | |
| SCHEMBL3086048 | 0.83 | HTR6 (0.42) | MEN1KMT2AALDH1A1HTR6KCNH2 | |
| SCHEMBL3094292 | 0.81 | MTNR1A (0.52) | HTR6HTR2CHTR2B | |
| SCHEMBL3093522 | 0.81 | MTNR1A (0.48) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL27769159 | 0.81 | HTR2C (0.41) | PTGDR2HTR6KCNH2ABCC9ABCC8 | |
| SCHEMBL3079742 | 0.81 | HTR6 (0.44) | HTR6KCNH2HTR2CHTR2BHTR2A | |
| SCHEMBL3081052 | 0.79 | CYP4F2 (0.43) | PTGDR2ALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL13180443 | 0.79 | HTR2A (0.40) | PTGDR2HTR6KCNH2ABCC9ABCC8 | |
| SCHEMBL3086603 | 0.79 | MTNR1A (0.60) | HTR6HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472885-A | Arylsulfonyl naphthalene derivatives and uses thereof | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | CN | disclosed |