Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 13/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769213 | 1.00 | DAO (0.40) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL29587840 | 0.81 | DAO (0.44) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL27748121 | 0.79 | DAO (0.40) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL19646802 | 0.78 | DRD2 (0.43) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL4734771 | 0.77 | DRD2 (0.47) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL1939638 | 0.75 | DRD2 (0.50) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL17413481 | 0.75 | DRD2 (0.45) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL17407617 | 0.72 | DRD2 (0.43) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL7411386 | 0.72 | DRD2 (0.49) | DAORIPK1DRD2DRD4DRD3 | |
| SCHEMBL13543890 | 0.72 | RIPK1 (0.58) | DAORIPK1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484454-A | Azaindole derivatives with a combination of partial nicotinic acetylcholine receptor agonism and dopamine reuptake inhibition | SOLVAY PHARM B V (NL) | 2009-07-15 | — | — | CN | claimed |
| CN-101484454-A | Azaindole derivatives with a combination of partial nicotinic acetylcholine receptor agonism and dopamine reuptake inhibition | SOLVAY PHARM B V (NL) | 2009-07-15 | — | — | CN | disclosed |